Life from an RNA World: The Ancestor Within

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Harvard University Press, 2010 - 198 էջ

A majority of evolutionary biologists believe that we now can envision our biological predecessorsâe"not the first, but nearly the first, living beings on Earth. Life from an RNA World is about these vanished forebears, sketching them in the distant past just as their workings first began to resemble our own. The advances that have made such a pursuit possible are rarely discussed outside of bio-labs. So here, says author Michael Yarus, is an album for interested non-biologists, an introduction to our relatives in deep time, slouching between the first rudimentary life on Earth and the appearance of more complex beings.

The era between, and the focus of Yarusâe(tm) work, is called the RNA world. It is RNA (ribonucleic acid) long believed to be a mere biologic copier and messenger, that offers us this glimpse into our ancient predecessors. To describe early RNA creatures, here called âeoeribocytesâe or RNA cells, Yarus deploys some basics of molecular biology. He reviews our current understanding of the tree of life, examines the structure of RNA itself, explains the operation of the genetic code, and covers much elseâe"all in an effort to reveal a departed biological world across billions of years between its heyday and ours.

Courting controversy among those who question the role of âeoeribocytesâe âe"citing the chemical fragility of RNA and the uncertainty about the origin of an RNA synthetic apparatusâe"Yarus offers an invaluable vision of early life on Earth. And his book makes that early form of life, our ancestor within, accessible to all of us.

 

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A Voluntary Chapter
1
The Buffalo and the Bacterium
5
No Jackalopes Please
13
A Dance of Atoms
30
The Origin of Life
36
The Winds That Blow through the Starry Ways
46
Tornados in a Junkyard
59
Between Genomes and Creatures
79
Intimations of an RNA World
109
The Experimentally Impaired Sciences
119
First Light
126
Interrogating
132
Replicase Activity
141
RNA Capabilities and the Origins
149
The Quest for the Peptidyl Transferase
155
The Ribocyte
176

A Thumbnail Molecular Biology
84
A Tape with a Shape
99
The Future of the RNA World
183
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Հեղինակի մասին (2010)

Michael Yarus is Professor Emeritus, Department of Molecular, Cellular, and Developmental Biology, University of Colorado.

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