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and tender, that it can scarcely bear to be touched. These cruptions after continuing some time totally disappear; the ulcers heal, and the itching ceases. The parents, on this account, highly flatter themselves with the hopes of these pests being quite vanished, never to return; but, in the course of a few months, they recur with equal severity: the itching and irritation take place night and day with scarcely any interval. This kind of visitation of the effects of cow-pox continues generally several years (unless some mercurial preparation be given): sometimes the disease is better, and sometimes worse. Glandular swellings, tumefied and ulcerated eye-lids, and violent inflammation of the coats of the eyes themselves, I have frequently found to follow vaccination. My friend Dr. Rowley, an experienced physician and general practitioner in medicine, and a man of veracity, in his treatise lately published, entitled,Cow-pox Inoculation no Security against the Small-pox Infection,' says, 'scabby eruptions, superficial abscesses, ulcers, boils, and suppurations in different parts; gangrene, and mortification about the ancles, and other parts of the body, I have been witness to.' He further observes, that Blindness and deafness have been not unfrequently the consequences of cow-pox inoculation, whether originating from the grease in horses, or the natural disease of cows.'

"These are some of the charming sequelæ of vaccination, or cow-pox inoculation. This practice has been boasted of as the greatest blessing to humanity, and was promised, with enthusiastic warmth, to be a perfect and perpetual security against the variolous infection, and a milder and safer disease than the smallpox inoculation. The fallacy of such promises brings to my recollection the story reported of Mr. Moore the almanack-måker, who, as he was riding over a very large common, on a nne day, in company with a friend, met with a shepherd who requested them to ride on, or they would be overtaken by a very great storin; and the old man predicted right, for before they got to the end of their journey he experienced as heavy a one as he ever knew, in which they both got pretty well soaked. Mr. Moore was determined to know, if possible, by what signs the shepherd knew it would rain, it being such fine weather a few hours before, consequently he rode back to sk him: because,' replied the old shep herd, Mr. Moore, in his almanack, promised it would be a very fine day.'

"3. Some children, ever since they were vaccinated, have been troubled with coughs, difliculty of breathing, and fevers of a slow and intermitting kind; their appetite has become diminished, their vivacity lost, the countenance pale, the flesh flabby; and a train of symptoms has ensued similar to those which always arise from an absorption of extraneous and poisonous matter:-In short, those children, who, before vaccination, were lively, strong, and had every appearance of

health, have become dull, weak, and censtantly ill, arising apparently from this matter being of a deleterious quality. In short, the small-pox, eruptions, and ulcerations, the constitutions being undermined, are three unfortunate circumstances so very frequent, and so well known, not only in every corner and street in London, but also in the different counties, to be subsequent and to arise from vaccination, that it becomes almost unneces sary to mention them; nor, indeed, should I deem it requisite, but my duty to my fellowcreatures induces me to endeavour to prevent such an evil in future. The vaccinators will not, they even cannot, at present adhere to truth, temper, and moderation, for they have promised too much, and have imposed too many falsehoods on the credulous for ther! to retract, without shame and disgrace. 1, therefore, most earnestly recommend the public, for whose benefit these observations are solely intended, to be influenced and guided by reason and facts only, and forbid in future vaccine inoculation being practised in their family, but return to the old, and well tried, and well-established practice, small-pox inoculation, in which will be found a perpetual security against variolous contagion, without undermining the constitution, or af fecting the body with any subsequent commplaints.

"To see these vaccinated children thus affected, some with eruptions and ulcers, others with coughs and fevers, and in other respects extremely ill, has rendered the pa rents very unhappy, and even miserable, not only from the present inconvenience, but also from these malignant complaints, arising froma this infection, being both tedious and difficult to eradicate. Shocking reflection to a hu mane mind! that a poison should be introduced into the human constitution without the plea of necessity, or the support of reason or experience, to make experiments, which the success of the small-pox inoculation had long ago rendered futile."

We learn, however, that these dreadful evils are not irremediable; we are ir formed that the disease may be eradicated by keeping the system for some weeks under the influence of mercury. If we do not misunderstand him he even recomall those who have been vaccinated, in mends that the plan should be pursued by order to remove from the system the la tent poison, which sooner or later will, break forth, and commit the ravages described above. Upon this proposal we make no comment.

The author next proceeds to enumerate the advantages of the small-pox inocula tion; he lays it down as an incontrover tible proposition, that in no case has the small-pox occurred twice in the same person, and almost asserts that the vario

lous inoculation, if properly conducted, can never prove fatal. So far from admitting that the disease is occasionally dangerous and productive of the most unpleasant effects, (occurrences which we adunit to be rare, but of the existence of which we cannot have the smallest doubt) he roundly asserts that "the small-pox inoculation produces no ill consequences whatever," and acquiring confidence as he advances, he next informs us that,

"The small-pox inoculation improves the health and constitution, and carries off many complaints which were very uncomfortable, both to the parents and children."

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The work concludes with some servations on inoculation of the smallpox," from which it appears that the author, although he has procured a diploma, and has been thus metamorphosed into a physician, has not forgotten his old trade of an apothecary.

ART. XIX.-Inoculation for the Small-pox vindicated; and its superior Efficacy and Safety to the Practice of Vaccination clearly proved. By GEORGE LIPSCOMB, Surgeon.

THE work commences with the following paragraph:

"The ferment of popular opinion respecting the cow-pox having, in some degree, subsided; and the torrent of fashion having been at length stemmed by the influences of reason and experience; the present time appears not altogether unfavourable to the introduction of a few remarks, which are designed to illustrate the arguments already adduced on the merits and consequences of vaccination; and to place in a clear and conspicuous point of view the fallacy of those doctrines by which the practice of it has been encouraged and supported."

We conceive the reasoning here employed is somewhat singular; he did not step forth to oppose the torrent of fashion and popular opinion, but waits until the mischief has been done, and the evil is now curing itself. Whether he was influenced by timidity or diffidence, it is not our business to inquire; our concern is not with his motives, but his pamphlet. The author takes it for granted, that there is before the public sufficient evidence to prove that vaccination is not a permanent security against the small-pox, and that it is sometimes followed by loathsome or even dangerous diseases. He appears to be a disciple and admirer of Dr. Squirrel, whose work he quotes with due respect, and whose hypothesis respecting the identity of the grease in horses and scrofula he assumes as an established point; he also lays it down without reserve, that the small-pox inoculation ought never to be fatal, and that no unpleasant consequences ever result from it if properly conducted.

Mr. Lipscomb sets out with lavish professions of candour, but he is one of that numerous tribe who may exclaim with Medea,

« ----video meliora proboque;
Deteriora sequor-"

promoters of vaccination with an attempt to impose upon the world.

"If I may be permitted to avow the dictates of my mind, I can conscientiously add, that it revolts with indignation at the shocking idea of thus wilfully imposing on the ignorant; of thus exposing to probable destruction those who regard us in the light of friendly advisers; of thus manifesting the disposition of faithless betrayers of the confidence reposed in the faculty as men of honour, integrity, and science. Was it by such insidious arts that the first rudiments of improvement were introduced into the world? Is it by such base and unworthy efforts that knowledge can be brought nearer to perfection? Rather let science perish than attempt to establish it on the ruins of justice and the wreck of truth!”

We must, however, admit the justice of our author's observations, when he points out the impropriety of trusting the vaccine inoculation in extra-professional

hands.

"Country clergymen, farmers, and old women, have been made the instruments for ascertaining the consequences of this important revolution in medical science. I would not be misunderstood as intending to give offence to either of these classes when I say, that however re-pectable, useful, and necesis impossible that any of them should have sary, they may be in their several stations, it been properly employed on this occasion: and greatly as I venerate and admire the learning and the moral worth of the clergy, greatly as I esteem and regard the honest and beneficial industry of the farmer, I cannot help thinking that less inischief has been done by the third description of persons above alJuded to, in the practice of vaccination, than by either of the other-because they have never published on the subject.”

We believe from this circumstance much evil has, and much more will arise; and we trust it may prove a lesson to medical men not to consider any part of their art so simple and unimportant, as to

for he very unequivocally charges the permit it to escape their attention.

10.

ART. XX.—A Dissertation on the Failure and Mischiefs of the Disease cailed the Cowpor, in which the principal Arguments adduced in Favour of l'accination, by Drs. Jenner, Pearson, Woodville, Lettsom, Thornton, and Adams, are examined, and confuted. By GEORGE LIPSCOMB, Surgeon. Svo. pp. 105.

JUST as we had finished our remarks upon the preceding article, a second pamphlet, from the pen of Mr. Lipscomb, was transmitted to us. We hoped to have met with some novelty, either of fact or argument, to make up for the deficiencies of the former: we have not, however, found this to be the case. The author commences as usual, with professions of candour, respect for genius, &c. &c.; he introduces observations upon the progress of error, the tendency in mankind to run after new doctrines, and other common-places of a similar nature. Our readers, we are confident, will pardon us for not laying before them a minute analysis of the work; we shall briefly notice its most prominent sentiments, from which an idea may be formed of the merits of the remainder.

The circumstance of the cow-pox being derived from a disease of the horse, seems to Mr. Lipscomb, from the first, an insufferable objection to its adoption.

"The cow-pox, necessarily connected with a morbid state of the fluids, and avowedly derived from the most polluted source,' could not be subjected to the judge ment of the faculty, unless that judgment were exerted to reject it altogether."

It is also urged, that the cow-pox is a new disease, and one with which we are consequently not thoroughly acquainted: its warmest advocates have not exactly coincided in all their opinions respecting it; they have differed about its origin, about its liability to recur in the same person, about the existence of the spurious disease, &c. The author strongly contends that the mortality of the inoculated smallpox is not so considerable as has been stated; and indeed very directly accuses those of ignorance in the management of their patients, who bave experienced a contrary result. He also positively denies that the small-pox can ever occur twice in the same person, and insinuates, that the cases which have been lately brought

forward in support of the contrary opinion, have been fabricated, for the purpose of undermining the public confidence in the small-pox inoculation. His great bugbear, however, appears to be the dreadful diseases that are left after vaccination. As usual, he does not condescend to go into particulars, but satisfies himself with referring to innumerable instances, which are sufficiently well known to every body.

Mr. Lipscomb is particularly disturbed with the attempts made by the friends of vaccination, to impress the benefits of the new practice upon the minds of the lower class of people; and expresses his high indignation at the oratorical language which has been adopted, on some occasions, in its behalf. Yet, strange inconsistency! while he will admit nothing but naked argument to be used in favour of vaccination, he is delighted with Dr. Moseley's wit and satire against it; and he can himself employ, in the saine cause, a strain of declamation, which, no doubt, he thinks We shall present our readers very fine. with one passage, which contains almost the only specimen of our author's powers of original observation.

"The subject is very indelicate and dis gusting, but I am compelled to notice partcularly one disease which has been delineated in Dr. Rowley's pamphlet, and described of this nature have come under my own obunder the title of the Ox-face. Two instances servation among numerous cases of other mor bid appearances, which were never seen in the human race before the unfortunate introduction of vaccination. In both these instances, the deformity was greatly heightened by a degree of strabismus which seems to constitute a characteristic of this singular malady; and forms a feature so striking, that Virgil's expression taurino vultu' would immediately occur to the classical observer, without even referring to the cause, or the descriptions which may have been given of the disease. But the Medical Journalists pronounce it to be a common abscess! Pour men! they are not very classical !”

ART. XXI.-Rogers on Cou-pox.

MANY of our readers will recollect that Mr. Cline and Mr. Birch, both surgeons of St. Thomas's hospital, when called upon to give their evidence respecting

cow-pox, before the committee appointed to examine Dr. Jenner's claim, differed considerably as to the probable utility of the new practice; while Mr. Chine gave

it his unqualified approbation, Mr. Birch was one of the very few who spoke doubt ingly upon its merits. Mr. Rogers, who was the pupil of the latter gentleman, comes forward to examine the grounds upon which these colleagues formed such different opinions; and endeavours to prove, not only that Mr. Birch had at that period enjoyed superior advantages for acquiring information on this subject, out that subsequent events had completely justified his dissent from the popular doctrine. He then proceeds to state it as his full conviction that the cow-pox has proved fatal. In confirmation of this assertion we do not perceive any new cases

brought forwards, the author conceiving that the public were already in possession of sufficient evidence. It will be seen that he differs from some of the writers whose works we have hitherto examined in respect to his second position; he does not think that vaccination produces scrofula, but new disease. The evidence upon which the author builds this opinion appears to us very slender; and as the result of his observation differs so widely in this particular point, even from that of some of the most zealous opposers of vaccination, we confess, that we think ourselves authorized in doubting its accuracy.

ART. XXII-Report of a Medical Committee on the Cases of supposed Small-Por after Vaccination, which occurred in Fullwood's Rents, Holborn, in August and September, 1804; with an Account of some subsequent Inoculations. 8vo. pp. 32.

OUR medical readers are no doubt acquainted with the outline of the facts which gave rise to this pamphlet. Two children who were vaccinated at the smallpos hospital, after an interval, one of two and the other of four years, were seized with what was said to be the small-pox; a respectable committee of medical men was accordingly formed, to examine and report upon the circumstances of the cases. The registers from the hospital, giving an account of their inoculation, are inserted, and the committee thought that there could be no doubt of the vaccine disease having gone through its proper course. They were influenced by the following considerations:

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First, the register of their cases, kept, as above, at the small-pox hospital: second, the declaration of Mr. Wachsel, resident inoculator at the hospital, who considers the appearances, and progress of vaccination, in these children, to have been perfectly regular and satisfactory: third, the cicatrices, or marks, remaining on their arms; which marks appear to the members of the committee to be such as are usually left after vaccine inoculation."

As to the other part of the inquiry, whether the subsequent disease was smallpox, the evidence appears no less direct. The complaint existed in the neighbourhood, and the children were repeatedly exposed to the infection; the one who was first taken ill was not indeed seen by the committee, but in the other at least, there was every reason to conclude that

the symptoms went through their usual course, and matter taken from the pustules communicated the small-pox to others. The committee conclude by fully admitting the fact of the small-pox having been received after vaccination, but they add,

"The above facts are not to be considerof vaccination. ed as militating against the general practice Some well authenticated, though rare cases, have been stated, in which the natural small-pox occurred twice in the same person. A few other instances are recorded of persons, who, after having undergone the inoculated small-pox, nevertheless took the disease by infection: yet these cases were not deemed conclusive against the advantages of variolous inoculation, nor do they seem to have impeded its progress.

"In every country where European science is diffused, the general preventive power of vaccine inoculation with regard to the small-pox, has been fully ascertained, and cannot now be affected by the result of,a few detached cases, which, by future observations and experiments, may be accounted for satisfactorily. The committee, therefore, with one accord, subscribes to the established opinion, that if vaccination were universally adopted, it would afford the means of finally exterminating the small-pox."

Many of our readers will, no doubt, be disposed to acquiesce in this opinion; but even those who dissent from it cannot but acknowledge that the pamphlet is written with candour, and the facts stated with perfect fairness.

1

ART. XXIII.-Observations on some late Attempts to depreciate the Value and Ejficacy of Vaccine Inoculation. By SAMUEL MERRIMAN. 8vo. pp. 35.

A principal object in this pamphlet is to expose the weakness of the reasoning, and the inaccuracy of the facts, brought forwards by Dr. Moseley. Perhaps the word reasoning can scarcely be applied to Dr. Moseley's work, as he appears to have thought the subject undeserving of a serious refutation, and consequently has attached to it only ridicule and sarcasin. It is not, however, by such weapons that a controversy of so much magnitude is to be decided. As to its power in securing the constitution against the small-pox, the author shows, that vaccination stands upon the same footing with the variolous inoculation; there are some few instances, after both the operations, where smallpox seems to have occurred; we must therefore either suppose in these rare instances, that the constitution is not secured, or if we feel reluctant to admit a deviation from so general a law, we must suppose that some irregularity in the conduct of the inoculated disease took place. But in whichever way we determine, the result will not be unfavorable to vacci

nation.

"At it never has been contended, that

the cow-pox was superior to the small-pox m its prophylactic virtues, its strongest advocates will be willing to admit the possibility that vaccination might fail where variolation coud not secure from re-infection."

It appears to have been admitted, ever in the time of Friend, that in those who have had small-pox, the application of variolous matter can produce pustules, which shall be capable of communicating the disease to others. These cases have not, however, been considered as a second occurrence of a mall-pox in the same person, but only as depending upon the local action of the variolous matter, eve though attended with some degree of constitutional affection. It is to be expected, that the same circumstance would take place after vaccination, but it would be unfair to denominate such cases instances of small-pox after cow-pox. Upon the whole, this little treatise is written with good-sense and candour, although we do not perceive that it contains any informa tion of which the public were not already in possession.

ART. XXIV.-An Address to the Medical Practitioners of Ireland, on the Subject of Cow-Pock. By SAMUEL B. LABATT, M. D. Licentiate of the College of Physicians, and Secretary to the Cow-Pock Institution, North Cope-street, Dublin. 8vo. pp. 140.

Dr. Labatt candidly acknowledges, that in the infancy of the practice mistakes must occasionally be expected to happen.

THE author regrets that, notwithstand- by precise experiments, the truth of this ing the numerous testimonies in favour of position; and to show, that the matter cow-pox, the practice of vaccination is might be communicated by inoculation still little known or attended to in Ire- from one human being to another, withland. Being fully persuaded of the be-out having its characteristic property denefits likely to accrue from its adoption, stroyed. but, at the same time, being aware of the nice discrimination which it is sometimes necessary to exercise in judging of the nature of the disease, he is anxious, not only to draw the attention of his countrymen to the subject, but to afford practitioners an accurate view of the phenomena which it exhibits. He begins by an historical sketch of its discovery: it ap-inoculation is now called in question. The pears to have been known in some other parts of England, as well as in Gloucestershire, likewise in the south of Ireland, in Holstein, Lombardy, and even in America; in all these places there existed some traditionary report of its proving a preservative against small-pox. It was, how ever, reserved for Dr. Jenner to prove,

"Whoever will take the trouble of looking into the history of small-pox inoculation, will find many more cases of failure recorded than have been attributed to cow-pock: yet we do not find that the efficacy of small-pox

celebrated Tissot, we are informed, having inoculated a favourite child, was satisfied with the appearances which followed, and therefore objected to a second inoculation; took the small-pox in the natural way, and unfortunately, however, the child afterwards fell a victim to it. In a pamphlet published in the year 1746, by a doctor Pierce Dodd, of London, we find two or three remarkable

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